GLP-1 therapy

GLP-1 Side Effects and How to Manage Them

March 24, 2026 · 5 min read

Nausea, fatigue, constipation, and the fixes that actually work.

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Most side effects are dose-paced

Slowing the titration schedule resolves the majority of complaints. There is no prize for reaching the top dose fastest.

The practical fixes

Smaller meals, more water, magnesium and fiber for constipation, and protein early in the day when appetite is highest.

When to call

Severe abdominal pain, persistent vomiting, or signs of dehydration warrant a same-day call, not a wait-and-see.

Related therapies

Keep reading

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